engleski

Clinical significance of microembolus detection by transcranial Doppler sonography in cardiovascular clinical conditions

SUMMARY Transcranial Doppler can detect microembolic signals which are charachterized by unidirectional high intensity increase, short duration, random occurrence, producing a "whistling" sound. Microembolic signals have been proven to represent solid or gaseous particles within the blood flow. Microemboli have been detected in a number of clinical cardiovascular settings ; carotid artery stenosis, aortic arch plaques, atrial fibrillation, myocardial infarction, prosthetic heart valves, patent foramen ovale, valvular stenosis, during invasive procedures (angiography, percutaneous transluminal angioplasty), surgery (carotid, cardiopulmonary bypass). Despite numerous studies performed so far, clinical significance of microembolic signals is still unclear. This article provides an overview of the development and current state of technical and clinical aspects of microembolus detection.

cerebral embolism ; ultrasonography ; pathophysiology ; cardiovascular pathology ; microemboli

doi:10.1016/j.ijsu.2005.12.001 2006 Surgical Associates Ltd Published by Elsevier Ltd