engleski

Etiological Background and Risk Factors of Chronic and Transient Atrial Fibrilation in Cantonal Hospital Zenica, Bosnia and Herzegovina

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia in developed countries. It is a disease of the elderly and it is common in patients (pts) with organic heart disease. Hypertension, hart failure and valvular heart disease are predisposing factors to AF. To evaluate relationship of different types of AF with under lying heart diseases and demographic characteristics of pts as well. From June 2000 to December 2005, 1520 consecutive pts with AF were studied during echocardiographic check-up. According to the 2-D transthoracic echocardiography pts were divided into groups based on dominative underlying heart diseases. Electrocardiographically documented AF was subdivided into two groups: transient and chronic. Binary logistic regression was used to investigate relationship between gender, age, hypertension, diabetes and underlying heart diseases with the type of AF. The median age was 70 years, ranged between 16 and 99 years. Chronic AF was noted in 1095 (72.4%) pts. 772 (51%) were men. Diabetes mellitus was found in 205 (13.6%) pts, among them, 120 (58.5%) were females. Hypertensive heart disease (HHD) was the most common underlying heart disease in pts with AF (33.9%) followed by dilatative cardiomiophaty (DCM), 23.2%, coronary heart disease (CHD), 19.4% and valvular heart disease (VHD), 16.2%. DCM was the oldest group (71± ; ; 9 years) with highest frequency of male pts (64%). On the other hand, VHD was mostly presented in females (63%) with mean age being one of the bottommost (65± ; ; 11 years) and accompanied by the lowest prevalence of DM (3.7%) compared to the surveyed population. Pts with underlying CHD had highest prevalence of DM (23%). Lone AF was diagnosed in only 2.7% pts, mostly in younger males (men 73%, average age 56± ; ; 13 years) A significant frequency of transient AF was observed in females (OR=1.28, 95% CI=1.00-1.64), younger pts (OR=1.04, 95% CI=1.02-1.05), pts with lone AF (OR=3.85, 95% CI=1.64-9.04) and in pts with hypertension regardless the presence of other concomitant heart diseases (OR=1.47, 95% CI=1.07-2.04). Chronic AF was usual in men, older pts, pts with DCM (OR=2.19, 95% CI=1.20-4.01) and VHD (OR=4.27, 95% CI=2.24-8.15). The presence of diabetes was not significantly related to any of two types of AF. HHD was by far the most prevalent associated medical condition. Chronic AF was predominant in groups with advanced cardiac remodeling such as DCM and VHD.

atrial fibrilation; risk factors

Liječnički vjesnik. Suplement (1330-4917) 128 (2006) (2) 3-162