engleski

Paraneoplastic Pemphigus in a Child without Malignancy.

Paraneoplastic pemphigus (PNP) is an autoimmune mucocutaneous disease mostly associated with specific beta-cell lymphoproliferative neoplasm. A 11-year-old boy presented to our department five years ago with erosions on oral mucosa, on the lips and with change on the conjunctiva. His skin was brownish-gray as it is seen in graft-versus-host disease - lichenoid type. Evaluation of underlying malignancy was done repeatedly but no malignancy was detected until today. Since demonstration of underlying, mostly lymphoproliferative, neoplasm is one of the minimal criteria for diagnosis of PNP there is question is this case paraneoplastic pemphigus or a new entity.

Paraneoplastic pemphigus; non-malignancy

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