engleski

EFFECTIVENESS OF OIL-BASED ADJUVANT FORMULATIONS CONTAINING PGM IN PRODUCTION OF PROTEIN-SPECIFIC POLYCLONAL ANTIBODIES

Results presented in this work are the clear demonstration of effectiveness of ISA206+PGM and ISA720 + PGM adjuvant formulations in inducing the protein-specific polyclonal antibodies in experimental rabbits. They also support our hypothesis that the adjuvant action of PGM could be improved in formulations that would prolong its availability in the mammalian organism. Incorporation of PGM into oil-based emulsions is perspective approach, that could exploit adjuvant effectivness of PGM.

adjuvants; Montanide ISA 720; Montanide ISA 206; peptidoglycan monomer

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