Bone structure of the iliac crest and lumbar spine: a histomorphometric study of adult population in Croatia (CROSBI ID 521951)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Cvijanović, Olga ; Kristofić, Ines ; Španjol, Josip ; Zoričić, Sanja ; Marić, Ivana ; Bobinac, Dragica
engleski
Bone structure of the iliac crest and lumbar spine: a histomorphometric study of adult population in Croatia
The aim of this study was to compare vertical 7 mm thick cylinders of vertebral (L3) and iliac trabecular bone (anterior, posterior, lateral) obtained from 40 normal cadavers aged from 40 to 80 years (20 females and 20 males). Undecalcified trabecular bone samples were embedded in MMA, cut in 7 microm thick sections and stained with TB and Goldner trichrome. Histomorphometric analysis was performed on an image analyzed (VAMS, Issa, zAGreb), and the following parameters were determined: Trabecular bone volume (BV/TV), surface density (BC/TV), trabecular thickness (Tb, Th), number (Tb.N) and separation (Tb.Sp), osteoid thickness (O.Th), volume (OV/BV) and surface (OS/BS). Iliac crest and lumbar vertebra bone samples were compared within each group and between different age-related groups. Men and women within the age range 60 to 80 yr had significantly increased O.Th (p<0.001), OV/BV (p<0.005) and OS/BS (p<0.001) in lumbar vertebrae. Moreover, Tb.S ((p<0.001) was higher in lumbar bone, while BV/TV (p<0.001) and Tb.Th (p<0.005) were greater in men iliac crest. BV/TV (p<0.05), BS/TV (p<0.001), and Tb.N (p<0.001), determined from both lumbar and iliac bone samples, were found significantly increased in a group of younger women (40-60 yr) while Tb.Sp (p<0.005) was lesser, when compared with a group of elderly women. Similarly, in a group of younger men we found BV/TV (p<0.001) and Tb.Th (p<0.005) greater while Tb.Sp (p<0.001) was lesser when compared to elderly men. These results indicate that age-related changes in bone microarchitecture more dramatically affect the vertebrae and less the iliac crest bone. We suggest that increased O.Th, OV/BV, OS/BS vertebral values in elderly women reflect the initial bone repairment, following trabecular microfractures.
bone histomorphometric parameters; iliac crest; lumbar spine; humans
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Podaci o prilogu
S197-S197.
2001.
nije evidentirano
objavljeno
Podaci o matičnoj publikaciji
Bone (New York, N.Y.)
Baron, Roland
New York (NY): Elsevier
8756-3282
Podaci o skupu
1st Joint Meeting of the International Bone and Mineral Society and the European Calcified Tissue Society
poster
05.06.2001-10.06.2001
Madrid, Španjolska