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Concomitant chemobrachyradiotherapy with ifosfamide and cisplatin followed by consolidation chemotherapy in the treatment of locally advanced adenocarcinoma or adenosquamous carcinoma of the cervix uteri. (CROSBI ID 127066)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Vrdoljak, Eduard ; Boraska Jelavić, Tihana ; Saratlija-Novaković, Zana ; Hamm, Wolfgang Concomitant chemobrachyradiotherapy with ifosfamide and cisplatin followed by consolidation chemotherapy in the treatment of locally advanced adenocarcinoma or adenosquamous carcinoma of the cervix uteri. // European journal of gynaecological oncology, 26 (2005), 6; 602-4-x

Podaci o odgovornosti

Vrdoljak, Eduard ; Boraska Jelavić, Tihana ; Saratlija-Novaković, Zana ; Hamm, Wolfgang

engleski

Concomitant chemobrachyradiotherapy with ifosfamide and cisplatin followed by consolidation chemotherapy in the treatment of locally advanced adenocarcinoma or adenosquamous carcinoma of the cervix uteri.

The optimal treatment of women with locally advanced adenocarcinoma or adenosquamous carcinoma of the cervix uteri is still undefined. We report a series of four consecutive patients with locally advanced adeno- or adenosquamous carcinomas of the uterine cervix (FIGO Stages IB-IIIB) treated by concomitant chemobrachyradiotherapy with ifosfamide and cisplatin followed by one to four cycles of consolidation chemotherapy with the same drug combination. After completion of this treatment all patients showed complete clinical remission. Now, after a median follow-up of 40 (range: 13.5-61) months all patients still present with no evidence of disease. Despite the low number of patients in this series we may conclude that concomitant chemobrachyradiotherapy with ifosfamide and cisplatin followed by consolidation chemotherapy with the same drug combination is an efficacious treatment of patients with locally advanced adeno- or adenosquamous carcinomas of the cervix uteri.

concomitant chemoradiation; ifosfamide; cisplatin; consolidation chemotherapy; adenocarcinoma of the cervix uteri; adenosquamous carcinoma of the cervix uteri

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Podaci o izdanju

26 (6)

2005.

602-4-x

objavljeno

0392-2936

Povezanost rada

Kliničke medicinske znanosti

Indeksiranost