Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Immunocomplex deposits in the skin of patients with multiple sclerosis (CROSBI ID 469915)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa

Matijaca, Meri ; Reić, Petar ; Marović, Anton ; Pavelin, Slobodan ; Sepčić, Juraj Immunocomplex deposits in the skin of patients with multiple sclerosis // Multiple sclerosis Clinical and Laboratory Research / Allen, Ingrid V. (ur.). Avenel (NJ): Stockton press, 1998. str. 286-x

Podaci o odgovornosti

Matijaca, Meri ; Reić, Petar ; Marović, Anton ; Pavelin, Slobodan ; Sepčić, Juraj

engleski

Immunocomplex deposits in the skin of patients with multiple sclerosis

In a group of 72 multiple sclerosis, MS, patients immunocomplex deposits at the dermal-epidermal junction were determined. Our aim was to compare the immunopathologic diagnosis based on a direct immunofluorescence, DIF, with clinical findings in these patients. Skin biopsy and DIF were performed according to Cormane method which was slighly modified by Gligora. Rabbit anti-human IgG, IgA, IgM and C3 antibodies were used. The youngest patient was 16 years old and the oldest was 52 years old, showing a female prevalence, 77.8 percent. DIF findings were negative for anti IgG antibodies in 59,7 percent, for anti IgA antibodies in 43 percent, for anti IgM antibodies in 18 percent, for anti C3 antibodies in 78 percent. Fluorescence of granular immunocomplex deposits on the dermal-epidermal junction was positive for anti IgG antibodies in 20,8 percent, for anti IgA antibodies in 50 percent, for anti IgM antibodies in 74 percent, for C3 antibodies in 9,7 percent. Clot forming fluorescence findings were positive for anti IgG antibodies in 15,3 percent, for anti IgA antibodies in 7 percent, for anti IgM antibodies in 8 percent, for anti C3 antibodies in 11 percent. DIF showed positive fluorescence of capillaries for anti IgG antibodies in 2,8 percent and for C3 antibodies in 1,3 percent. DIF showed positive fluorescence of citobodies for anti IgG antibodies in 1,4 percent. Results sugest that the most inportant findings were fluorescence of anti IgM antibodies forming granular immunocomplex deposits.

Multiple sclerosis; Immunocomplex; Immunofluorescence-direct

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

286-x.

1998.

nije evidentirano

objavljeno

Podaci o matičnoj publikaciji

Multiple sclerosis Clinical and Laboratory Research

Allen, Ingrid V.

Avenel (NJ): Stockton press

Podaci o skupu

ECTRIMS 98 14th Congress of the European Committee for Treatment and Research in Multiple Sclerosis

poster

09.09.1998-12.09.1998

Stockholm, Švedska

Povezanost rada

Javno zdravstvo i zdravstvena zaštita