engleski

Significance of proliferative epithelial changes in breast fine-needle aspiration

The authors analyzed 6439 fine-needle aspirations(FNA).The total number of FNA performed per year at the authors institution was found to be increasing.The authors analyzed the numbers of carcinomas and proliferative breast alterations separately. A statistically significant increase was recorded in the group of aspirate specimens that had epithelial proliferation ; the increase was greater than that seen in aspirate specimens with normal epithelium (p<0.001). Biopsy was recommended in 151 of 6439 (2.3%)FNA and performed for 67 of the 151 recommendations.Cytologic findings were compared with pathohistologic findings.A histologic carcinoma was found in 14 of 67(20.8%)patients who had biopsy performed.The authors concluded that clinicians should give particular attention to atypia in cytologic aspirate specimens.

breast FNA ; proliferative changes ; cytologic atypia

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