engleski

Alpha-adrenergic receptor responsiveness is preserved during prolonged exercise

These results demonstrate that a1- and a2- adrenergic receptor responsiveness to infusion of selective a1- and a2- adrenergic receptor agonists and endogenous norepinephrine release (tyramine) does not decline during prolonged mild-intensity exercise. Thus a decrease in a-adrenergic receptor responsiveness over time does not appear to be responsible for the decrease in sympathetic restraint of muscle blood flow during prolonged exercise.

vascular conductance; sympathetic nervous system; skeletal muscle; blood flow; functional sympatholysis

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