Biphenotype acute leukaemia with translocation t(3 ; 7)(q21 ; q34-35) (CROSBI ID 470955)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Mrsić, Sanja ; Batinić, Drago ; Boban, Dubravka ; Marković-Glamočak, Mirjana ; Sučić, Mirna ; Stavljenić-Rukavina, Ana ; Labar, Boris
engleski
Biphenotype acute leukaemia with translocation t(3 ; 7)(q21 ; q34-35)
Biphenotype acute leukaemia is a very rare type of leukaemia characterized by the oresence of myeloid and lymphoid markers. In this paper we describe a patient with acute leukaemia (AL) consisting of two cell-populations, one expressing CD34, HLA-DR and cytoplasmic CD3, and the other expressing myeloid marker CD13 and cytoplasmic CD3. Cytochemical analysis revealed 10% MPO+ cells and 70% PAS+ cells. Cytogenetic showed 46xx, T(3 ; 7)(q21 ; q34-35). This unique finding is of special interest since 3q21 has been seen in AML patients with abnormal platelets while 7q34-35 has been associated with TCR locus and associated with ALL.
Biphenotypic leukemia ; cytogenetics
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Podaci o prilogu
78-78-x.
1996.
objavljeno
Podaci o matičnoj publikaciji
Fourth seminar New Trends in the Treatment of Acute Leukaemia
Mrsić, Mirando ; Labar, Boris
Zagreb: University Hospital Rebro Zagreb and European School of Oncology
Podaci o skupu
Fourth seminar New Trends in the Treatment of Acute Leukaemia
poster
14.09.1996-17.09.1996
Brijuni, Hrvatska