A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia (CROSBI ID 134985)
Prilog u časopisu | Pismo (znanstveno) | međunarodna recenzija
Podaci o odgovornosti
Antica, Mariastefania ; Dubravčić, Klara ; Weber, Igor ; Rajić, Ljubica ; Labar, Boris ; Batinić, Drago
engleski
A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia
We examined whether phosphorylation of Aiolos in primary human lymphocytes is part of the malignant transformation in leukemia. By analyzing mutations at a restriction site we show here that impairment of Aiolos activity in human leukemia is not based on deficient phosphorylation as had been demonstrated in experiments in vitro.
leukemia; Aiolos; transcription factors
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Podaci o izdanju
Povezanost rada
Temeljne medicinske znanosti, Biologija