Variations in the risk of gastrointestinal hemorrhage with non-steroidal anti-inflammatory drugs and localization of lesions (CROSBI ID 84438)
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Podaci o odgovornosti
Pulanić, Roland ; Dubravčić, Dubravka ; Ostojić-Pulanić, Branka ; Vrhovac, Božidar
engleski
Variations in the risk of gastrointestinal hemorrhage with non-steroidal anti-inflammatory drugs and localization of lesions
The aim of this prospective study was to determine the effect of ulcerogenic drugs in patients with bleeding peptic ulcers and erosions with respect to their age and sex, ulcer histoty and additional risk factors such as family medical history, alcohol use, smoking, coffe consumption and stress. In this study, there was no death from ulcer disease with NSAID use. It may be concluded that NSAIDs are acommon cause of damage to gastroduodenal mucosa. The risk of drug therapy should be balanced against the risk of the disease.
non-steroidal anti-inflammatory drugs; bleeding peptic ulcers; additional risk factors; localization of lesions
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