engleski

Candida species susceptibility to fluconazole in patients with oral symptoms

Objective: The aim of the study was to determine susceptibility of Candida species collected from oral cavity from patients with dry mouth and burning mouth syndrome. Method: This study examined the oral yeast colonization in 104 participants. Samples were collected with tongue swabs and cultured on Sabouraud's dextrose agar. All isolates were identified by germ tube production, chlamydospore development on cornmeal agar with 0, 5% Tween 80 (Difco, Detroit, USA) and ID 32 Candida identification kit (bio-Merieux, Marcy-l'Etoile, France). The susceptibility profile was evaluated by Etest (AB BIODISK, Solna, Sweden). Results: At the time of sampling, 30 (28, 84%) individuals were colonized with Candida species. The mean minimally inhibitory concentration was 0, 34&plusmn ; 0, 22 μ g/mL (0, 125-1 μ g/mL). All the isolates were susceptible to fluconazole. Conclusion: Since all the isolates were susceptible, fluconazole can be safely used for treatment of oral candidiasis in this group of patients.

oral symptoms; fluconazole; candida

nije evidentirano