Stimulation of hematopoiesis by a water - soluble derivative of propolis in mice (CROSBI ID 136555)
Prilog u časopisu | izvorni znanstveni rad
Podaci o odgovornosti
Oršolić, Nada ; Tadić, Zoran ; Benković, Vesna ; Horvat, Anica ; Lisičić, Duje ; Bašić, Ivan
engleski
Stimulation of hematopoiesis by a water - soluble derivative of propolis in mice
We have investigated the effect of water - soluble derivative of propolis (WSDP) on hematopoiesis of CBA mice using exogenous spleen colony assay (CFUs assay). Given perorally (po) 50 mg / kg to mice for 20 consecutive days WSDP increased the number of exogenous CFUs as compared to control. WSDP given either for 20 or 40 days elevated the number of cells in hematopoietic tissue and increased the number of leucocytes in peripheral blood ; prolonged treatment with WSDP also elevated histological appearance of myeloid and megakaryocytic types of CFUs.
Colony forming units (CFUs); Hematopoiesis; Mice; Propolis
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