engleski

Surface marker analysis in routine laboratory classification/diagnosis of leukaemia

The usefulness of a panel of monoclonal antibodies against leucocyte surface antigens - Tll/CD2, Tl/CD5, B4/CD19, B1/CD20, CALLA/CD 10, My9/CD33 and Ia/DR - was assessed in routine classification in the diagnosis of leukaemia. Eighty leukaemic patients aged >15 yr were divided into two groups: 56 selected patients diagnosed before immunological typing, and 24 patients with provisional diagnosis of acute leukaemia. The panel used delineated the blast origin in the majority of patients and selected those requiring further testing in a specialized center.

Immunological phenotyping; classification of leukaemia

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