Synthesis of the novel 2, 3-epoxypropyl and 3-amino-2-hydroxypropyl derivatives of purine and pyrimidine bases (CROSBI ID 471247)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Raić, Silvana ; Vikić-Topić, Dražen ; Mintas, Mladen
engleski
Synthesis of the novel 2, 3-epoxypropyl and 3-amino-2-hydroxypropyl derivatives of purine and pyrimidine bases
A large number of acyclic nucleoside analogues have been synthesized due to their potential activities as antiviral agents. In this connection and related to our previous studies on modified nucleoside analogues, we have prepared novel purine and pyrimidine nucleoside analogues containing 2, 3-epoxypropyl (I and II) and 3-amino-2-hydroxypropyl (III and IV) side chains. The site of alkylation of the purine ring was determined by 1H and 13C NMR spectra on the basis of chemical shifts, coupling constants and connectivities in NOESY and heteronuclear correlation spectra.
2; 3-epoxypropyl and 3-amino-2-hydroxypropyl derivatives of purine and pyrimidine bases; antiviral agents; heteronuclear correlation spectra
Rad je kao poster prezentiran i na skupu XIIIth International Round Table , Nucleosides, Nucleotides and Their Biological Applications, održanom od 06.-10.09.1998., Montpellier, Francuska ; uz međunarodnu recenziju objavljen u Knjizi sažetaka ; 1998. ; str. 72-72.
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
44-44.
1998.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
Dubrovnik International Course & Conference on the Interfaces among Mathematics, Chemistry and Computer Sciences (13 ; 1998)
poster
22.06.1998-27.06.1998
Dubrovnik, Hrvatska