engleski

Are serum lipids measured on stroke admission prognostic?

Background: It has been hypothesized that serum lipids measured in early period of stroke are predictive of stroke severity and outcome. The optimal time for lipid measurement is not established. We explored whether lipid profile assessed within the first 24 hours after stroke onset: (i) differs from stroke-free individuals ; (ii) differs between stroke subtypes and (iii) is predictive of stroke severity and outcome. Methods: We prospectively enrolled 70 acute ischemic stroke patients who presented to the Stroke Unit within the 24 hours of the onset of stroke symptoms, and 68 stroke-free controls. Results: Triglycerides (P<0.001) and HDL cholesterol (P<0.001) were significantly lower in patients, than in controls. HDL cholesterol was different across stroke subtypes classified according to TOAST scale (P=0.035). Patients with more severe stroke had higher serum triglycerides (OR 2.755 ; P=0.030). Conclusions: Serum triglycerides might serve as a prognostic marker in acute stroke patient.

cerebrovascular accident; cholesterol; lipid profile; prognosis; triglycerides

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