engleski

European surveillance study on antimicrobial susceptibility of Gram-positive anaerobic cocci

Gram-positive anaerobic cocci (GPAC) are heterogenous group of microorganisms frequently isolated from local and systemic infcetions. In this study, the antimicrobial susceptibilities of clinical strains isolated in 10 European countries were investigated. After identification of 299 GPAC to species level, the minimum inhibitory concentrations of penicillin, imipenem, clindamycin, metronidazole, vancomycin and linezolid were determined by the agar dilution method according to the Clinical Laboratory Standards Institute. The majority of isolates were identified as Finegoldia magna and Parvomonas micra (formerly Peptostreptococcus micros), isolated from skin and soft tissue infections. All isolates were susceptible to imipenem, metronidazole, vancomycin and linezolid. Twenty-one isolates (7%) were resistant to penicillin (n=13) and/or to clindamycin (n=12). Four isolates were resistant to both agents. The majority of resistant isolates were identified as F. magna and originated from blood, abscesses and soft tissue infections.

antimicrobial resistance; clinical isolates; anaerobic cocci

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