A Systems Biology Markup Language Model of a T-Cell Receptor Activated Signal Transduction Network (CROSBI ID 537800)
Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Tušek, Ana ; Lorenz Müller, Christian ; Supper, Jochen ; Zell, Andreas ; Kurtanjek Želimir ; Sbalzarini, Ivo
engleski
A Systems Biology Markup Language Model of a T-Cell Receptor Activated Signal Transduction Network
Application of system theory in biology has led to development of computer languages for mathematical modeling which are in open source and apply common standards for model transplatform exchangeability and integration with extensive model banks, databases, numerical and statistical methods and graphical tools. Standardization has led to Systems Biology Markup Language (SBML) based on XML format, while open source policy enables integration of computer resources and provide synergistic integration of scientific results and methodologies from various scientific fields. Different software projects are have been ini-tiated resulting in software such as: SBToolbox, JDesigner, SBWorkbench (SBW), and CellDesigner. The main use of the systems biology software is to investigate biochemical networks, gene regulatory networks, signal transduction, cell communication, dynamical complex behavior, and most importantly to lead to understanding of life regulation. In this work is presented use of CellDesigner language and modeling tools applied for analysis of signal transduction in T-cell as a part of a human immunity system.
SBML; T-cell receptor; signal transduction.
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Podaci o prilogu
651-658.
2007.
objavljeno
Podaci o matičnoj publikaciji
Proceedings of the ITI 2007 29 th Int. Conf. on Information Technology Interfaces
Editor Vesna Luzar-Stiffler, Vesna Hljuz-Dobrić
Zagreb: Sveučilišni računski centar Sveučilišta u Zagrebu (Srce)
1330-1012
Podaci o skupu
ITI 2007 29 th Int. Conf. on Information Technology Interfaces
predavanje
25.06.2007-28.06.2007
Cavtat, Hrvatska