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Diffusing capacity in patients with GERD (CROSBI ID 538801)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa

Bazina, Antonela ; Turkalj, Mirjana ; Plavec, Davor ; Ćaleta, Drago ; Vlašić, Željka ; Erceg, Damir ; Nogalo, Boro Diffusing capacity in patients with GERD // Allergy : european journal of allergy and clinical immunology. 2007. str. 417-417

Podaci o odgovornosti

Bazina, Antonela ; Turkalj, Mirjana ; Plavec, Davor ; Ćaleta, Drago ; Vlašić, Željka ; Erceg, Damir ; Nogalo, Boro

engleski

Diffusing capacity in patients with GERD

Gastroesophageal reflux (GER) is associated with respiratory diseases, particularly with asthma and chronic posterior laryngitis. Continuous aspiration of acid or bulk fluid in to the airways can cause chronic inflammation in the lung parenchyma and alveolar tissue. In the airways it may also cause airway obstruction and gas exchange impairment. To assess the influence of gastroesophageal reflux on lung function and gas diffusion capacity in children with asthma and chronic laryngitis. In 22 children (8– 17 years, both sexes, BMI 16– 27.2) with asthma and chronic laryngitis suggestive for GER, 24-h pH probe was administered. Detailed history, clinical examination, lung function testing, diffusing capacity for CO (DLCO), body pletismography, FENO were performed in all patients during the same visit. All patients were positive for GER (either positive fraction time with pHo4, Boix-Ochoa score, or Johnson-DeMeesters score). DLCO ranged 74– 128% and FENO 6.4– 54.3 ppb. Inverse correlation was found for all reflux indexes with DLCO (_0.71, _0.71, _0.76 ; Po0.001 for all, respectively). Patients with severe reflux (greater than median) had significantly lower values of DLCO (Po0.001). No association was found between reflux indexes and lung function parameters, FENO or BMI. Our results suggest that in patients with significant GER, DLCO should be measured because their dyspnea could be related to gas exchange impairment, despite normal lung function.

diffusing capacity; GERD

doi: 10.1111/j.1398-9995.2007.01407.x

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

417-417.

2007.

nije evidentirano

objavljeno

Podaci o matičnoj publikaciji

Allergy : european journal of allergy and clinical immunology

Gothenburg:

0105-4538

Podaci o skupu

Pediatric Asthma

poster

09.06.2007-13.06.2007

Göteborg, Švedska

Povezanost rada

Kliničke medicinske znanosti, Farmacija

Indeksiranost