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Reproductive hormones in men with respect to blood lead and cadmium levels (CROSBI ID 539558)

Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija

Telišman, Spomenka ; Cvitković, Petar ; Ročić, Boris ; Prpić-Majić, Danica ; Pizent, Alica Reproductive hormones in men with respect to blood lead and cadmium levels // Heavy Metals in the Environment / Farmer, JG (ur.). Edinburgh: CEP Consultants, 1991. str. 13-16

Podaci o odgovornosti

Telišman, Spomenka ; Cvitković, Petar ; Ročić, Boris ; Prpić-Majić, Danica ; Pizent, Alica

engleski

Reproductive hormones in men with respect to blood lead and cadmium levels

Follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, and estradiol were measured in the serum of 152 male volunteers: 51 subjects with no occupational exposure to lead or cadmium, and 101 subjects with slight to excessive occupational exposure to lead. Lead exposure assessment included: blood lead (PbB), activity of erythrocyte delta-aminolevulinic acid dehydratase (ALAD), and erythrocyte protoporphyrin (EP). Possible confounding factors: age, smoking habits, alcohol consumption, serum zinc (ZnS), serum copper (CuS), and blood cadmium (CdB) were evaluated. The results showed slight increases in testosterone and estradiol with respect to an increase in lead exposure (PbB, ALAD, EP), which remained significant after controlling for age, ZnS, CuS, CdB (which highly correlated with smoking habit), and alcohol consumption. Cigarette smoking/cadmium and alcohol consumption were found to somewhat influence the level of hormones. However, no impairment of male reproductive endocrine function was observed. With regard to the observed lead-induced decrease in sperm count in the same subjects, the results are in favour of our hypothesis of an increase in sperm destruction, rather than a decrease in sperm production, with respect to the increase in lead exposure in men.

Reproductive hormones in men; blood lead; blood cadmium

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Podaci o prilogu

13-16.

1991.

objavljeno

Podaci o matičnoj publikaciji

Heavy Metals in the Environment

Farmer, JG

Edinburgh: CEP Consultants

0 905941 47 0

Podaci o skupu

The 8th International Conference on Heavy Metals in the Environment

predavanje

01.01.1991-01.01.1991

Edinburgh, Ujedinjeno Kraljevstvo

Povezanost rada

Javno zdravstvo i zdravstvena zaštita