engleski

Rocuronium attenuates oculocardiac reflex during squint surgery in children anesthetized with halothane and nitrous oxide.

Background and Goal of the Study: The occulocardiac reflex (OCR) appears frequently during squint surgery. Different neuromuscular relaxants have been studied for the prevention of OCR, but not rocuronium. The goal of this controlled and prospective study was to test the possibility of preventing the OCR with 0.4 mg/kg-1 of rocuronium. Materials and Methods: ASA 1 children, 9 through 10 years old (5.7± ; 1.9, mean± ; SD), undergoing surgery of the medial rectus muscle (MRM) were randomly assigned to two groups. In the R group (rocuronium, n=59), 0.4 mg/kg-1 of rocuronium was administered intravenously before intubation. In the C group (control, n=60), no muscle relaxant was used. The anesthesia was induced and maintained with halothane and N2O/O2 (50/60%). The OCR was defined as a ≥ 15% reduction in hearth rate and/or appearance of any arrhythmias after manipulation with MRM. ANOVA, Chi-square (with Yates correction), and t-test were used for statistical analysis ; p<0.05 was considered statistically significant. Results and Discussion: There was no difference between groups regarding gender (p=0.77), age (p=0.17), body mass (p=0.77), ET halothane (p=0.72), or duration of surgery (p=0.75), and anesthesia (p=0.67). In the R group, the incidence of sole arrhythmias and total OCR was decreased, but not of sole bradycardias and bradyarrhythmias. Conclusion: Rocuronium 0.4 mg/kg-1 decreased the OCR occurrence in children undergoing surgery of MRM in halothane anesthesia by reducing the incidence of supraventricular and ventriculare premature beats.

rocuronium; oculocardiac reflex; anesthesia

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