engleski

General and disease-specific health related quality of life of patients with inflammatory and functional bowel disease

Health related quality of life (HRQOL) is a concept that has developed from the need to estimate the impact of chronic diseases and to predict daily function and well-being based on subjective attitudes and experiences of physical, social and emotional health. The primary aim of this study was to investigate the relation between general and disease-specific health related quality of life of patients with inflammatory and functional bowel disease. The secondary aim was to compare general helath-related quality of life among patients (IBD and IBS) and healthy control. About 100 outpatients of the Gastroenterology Department, Clinical Hospital Centre Rijeka, would participate in this study. There would be cca. 50 patients with inflammatory bowel diseases and 50 patients with irritable bowel syndrome, as well as 50 healthy persons, aged 18 to 65. In the period from January to May 2008, the participants would fill the questionnaires (The Medical Outcome Study Short-Form 36 (SF-36), Inflammatory Bowel Disease Questionnaire (IBDQ), Irritable Bowel Syndrome Quality of Life Questionnaire (IBS-36), and General Data Questionnaire). We expect that the general and disease-specific HRQOL would be strongly interconnected and patients with high score on disease-specific health-related quality of life questionnaire (higher score indicated worse disease-specific HRQOL) would have low general HRQOL. Also, there would be no significant differences in measured variables between patients with inflammatory bowel disease (ulcerative colitis and Crohn’ s disease) and functional bowel disorder (Irritable bowel syndrome) but there would be significant differences in general health related quality of life between patients and healthy control. The present study would show that the disease specific qestionnaires are complementary to generic questionnaire and these two types of instruments could be used collectively or separately depend on the purpose of the investigation. Progress is still to be made in improving quality of life for patients with IBD and IBS and to achieve this health care professionals should aim to incorporate basic quality of life assessment into patient’s consultations.

health related quality of life; inflammatory bowel diseases; irritable bowel syndrome

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