engleski

Lamotrigine in the treatment of pain syndromes and neuropathic pain

Anti-epileptic drugs are increasingly used in the treatment ofapin syndromes and neuropathic pain. Sodium channel blockers can be effective in the treatment of pain. The object of our interest is the efficiency of lamotrigine in treating the pain. A MEDLINE search was conducted to identify patient studies, case reports, letters, and reviews in Englisch published from 1986 to May 2007. The search has indicated efficiency in treating a number of painful syndromes and neuropathic pain ; central pain, trigeminal neuralgia and trigeminal neuralgia in multiple sclerosis, pain in multiple sclerosis, SUNCT syndrome, cluster headache, glossopharyngeal neuralgia, neuropathic pain, allodynia, neuralgia after nervesection, postherpetic neuralgia, HIV- associated neuropathy. Further researches are required on the role of lamotrigine in treating the spinal cord injury pain, neuralgia after nerve section, postoperative analgesic requirement, and in migraine.

lamotrigine ; pain ; neuralgia

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