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Magnesium and calcium in exhaled breath condensate of children with asthma and gastroesophageal reflux disease (CROSBI ID 146819)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Dodig, Slavica ; Vlašić, Željka ; Čepelak, Ivana ; Zrinski Topić, Renata ; Turkalj, Mirjana ; Nogalo, Boro Magnesium and calcium in exhaled breath condensate of children with asthma and gastroesophageal reflux disease // Journal of clinical laboratory analysis, 23 (2009), 1; 34-39. doi: 10.1002/jcla.20286

Podaci o odgovornosti

Dodig, Slavica ; Vlašić, Željka ; Čepelak, Ivana ; Zrinski Topić, Renata ; Turkalj, Mirjana ; Nogalo, Boro

engleski

Magnesium and calcium in exhaled breath condensate of children with asthma and gastroesophageal reflux disease

Magnesium and calcium physiologic functions are closely related. Magnesium is primarily an intracellular cation, the action of which also involves maintenance of cellular ionic balance, while influencing calcium homeostasis by blocking calcium channels. The aim of this study was to compare the concentrations of magnesium and calcium in exhaled breath condensate (EBC) of children with asthma and gastroesophageal reflux disease (GERD). EBC was collected from 66 children aged 7-14 years (23 children with acute asthma, 17 children with GERD, and 26 healthy children). Determination of magnesium and calciumconcentrations was preceded by optimization and validation for low concentrations. No difference was recorded for either magnesium or calcium concentration between study groups. However, the magnesium to calcium ratio was statistically significantly lower in both GERD and asthma children as compared with control group. Study results showed the magnesium to calcium ratio to be a statistically significantly better indicator of certain pathologic changes than absolute concentration of either ion.

asthma; calcium; exhaled breath condensate; gastroesophageal reflux disease; magnesium

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Podaci o izdanju

23 (1)

2009.

34-39

objavljeno

0887-8013

10.1002/jcla.20286

Povezanost rada

Temeljne medicinske znanosti, Kliničke medicinske znanosti, Farmacija

Poveznice
Indeksiranost