engleski

Hospital analysis of the central nervous system drug utilization during two periods

This study analyses the drugs used for the central nervous system (ATC- N drug group) over two 4-year periods (the first one from 1996-1999 and the second from 2001-2004) in the University Hospital Centre, Rijeka, Croatia. The aim was to detect and compare the most frequently prescribed drugs in the ATC-N group and to analyse the use of each of these drugs financially. The use of the drugs was evaluated according to defined daily doses (DDD) per 100 bed-days and financially in Euro per 100 bed-days. The most frequently prescribed drug in both periods from the N-group was diazepam (mean value of 30.22 and 25.01 DDD/100 bed-days) and the three other drugs from benzodiazepine group (oxazeparn, midazolam and nitrazepam) are among the first ten most frequently prescribed drugs. Financially, diazepam was the second in the first period (5.9 Euro/100 bed-days) and the sixth in the second one (3.25). The first three in the second period, according to financial consumption were fentanyl(29.15), fluphenazine (8.25) and tramadol (5.05) which was the first in the first period (14.4). In both periods metamizol was among the ten most frequently prescribed drugs but in a decreasing trend (3.8 and 1.55). This study showed the prescribing habits and their financial consequences. According to the results there are several possible fields for further investigation and therapeutic rationalisation especially concerning the benzodiazepine group and the group of analgetics.

hospital analysis; ATC- N drug group; DDD

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