engleski

Genetic instability and the biotechnology of Streptomyces

Genetic instability is very common in Streptomyces species. The phenotypic and genetic bases of instability are reviewed and the question of whether there is a common mechanism for all forms of instability is discussed. The phenomenon of "reversion" of deletion mutations is considered in the context of a model that distinguishes the genetic content of mycelium and spores.

streptomyces; deletion; DNA amplification; insertion sequence

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