engleski

bla(CTX-M) Genes in Escherichia coli Strains from Croatian Hospitals Are Located in New (bla(CTX-M-3a)) and Widely Spread (bla(CTX-M-3a) and bla(CTX-M-15)) Genetic Structures

CTX-M-producing Escherichia coli isolates from three Croatian hospitals were analyzed. All blaCTX-M-15 and one blaCTX-M-3a genes resided in widely-spread ISEcp1 transposition modules but other blaCTX-M-3a genes were in a new configuration with two IS26 copies, indicating a new event of gene mobilization from a Kluyvera ascorbata genome. The study confirmed the role of E. coli ST131 clonal group with IncFII-type plasmids in the spread of blaCTX-M-15, and of IncL/M pCTX-M3-type plasmids in dissemination of blaCTX-M-3a.

Eschericia coli; CTX-M beta-lactamases; cefotaxime resistance

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