engleski

Prevalence and characteristics of cerebrovascular atherosclerotic disease in patients with diabetes mellitus type 2

A great number of epidemiological studies confirms that diabetes is an independent risk factor for stroke. Some studies cause doubt that atherosclerotic changes are heavier in diabetics than in general population. In our study we analysed prevalence and characteristics of cerebrovascular aherosclerotic disease in patients with diabetes mellitus type 2. The study included 60 persons of both gender with confirmed diabetes mellitus type 2 . The control group consisted of 60 healthy subjects, similar age as persons with diabetes. The investigation included color dopler flow imaging (CDFI) of extracranial arteries and transcranial dopler (TCD) of intracranial cerebral arteries. The analysis of frequency of atherosclerotic cerebrovascular desease showed statistically significant more prevalence in the group of examinees compared to the control group. In the group of examinees we found statistically significant more patologic findings (p<0.01) on carotid arteries and arteries of the circle of Willis. Atherosclerotic changes were statistically significant more severe (p<0.05) in the group of examinees compared to control group. Among examinees we found stronger degree of carotid stenoses and other signs of cerebral macroangiopathy, as well as signs of cerebral microangiopathy. According to our results we concluded that diabetes mellitus laeds to earlier and faster development of the atherosclerotic cerebrovascular disease, influnces the cerebral hemodinamic and increases the risk of stroke.

epidemiology; prevalence; diabetes mellitus type 2; carotid artery disease; atherosclerosis

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