Antioxidant PBN ameliorates the teratogenic influence of 5-azacytidine in the rat (CROSBI ID 550837)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Sobočan, Nikola ; Sinčić, Nino ; Katušić, Ana ; Šerman, Ljiljana ; Nikuševa-Martić, Tamara ; Jurić-Lekić, Gordana ; Paić, Frane ; Vlahović, Maja ; Bulić-Jakuš, Floriana
engleski
Antioxidant PBN ameliorates the teratogenic influence of 5-azacytidine in the rat
Influence of the antioxidant N– tert– Butyl– α – phenylnitron (PBN) on teratogenesis induced by the DNA demethylating agent 5-azacytidine (5azaC) was investigated in the rat. Here we present data where PBN significantly improved most of developmental parameters when used as a pretreatment to 5azaC which can lead to conclusion that the teratogenic impact of 5azaC could at least partially depend on activation of oxidative stress pathways.
PBN; 5-azacytidine; antioxidans; rat
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Podaci o prilogu
15-15.
2009.
objavljeno
Podaci o matičnoj publikaciji
Conference papers of 20th Ljudevit Jurak International Symposium on Comparative Pathology
Zagreb:
Podaci o skupu
20th Ljudevit Jurak international symposium on comparative pathology
predavanje
05.06.2009-06.06.2009
Zagreb, Hrvatska
