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izvor podataka: crosbi

Cerebellar glioblastomas : pathophysiology, clinical presentation and management (CROSBI ID 152658)

Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija

Grahovac, Gordan ; Tomac, Damir ; Lambaša, Smiljka ; Zorić, Arijana ; Habek, Mario Cerebellar glioblastomas : pathophysiology, clinical presentation and management // Acta neurochirurgica, 151 (2009), 6; 653-657

Podaci o odgovornosti

Grahovac, Gordan ; Tomac, Damir ; Lambaša, Smiljka ; Zorić, Arijana ; Habek, Mario

engleski

Cerebellar glioblastomas : pathophysiology, clinical presentation and management

Glioblastoma multiforme usually affects the cerebral hemispheres with the peak age of onset in the sixth or seventh decade, while cerebellar glioblastoma multiforme is a rare tumour especially in younger patients. Most result from de-differentiation from low grade astrocytoma (secondary glioblastoma) or can develop de novo (primary glioblastoma). Primary glioblastomas develop in older patients while secondary glioblastomas develop in younger patients and contain TP53 mutations as the earliest detectable change. We report a 28 year old patient with primary multi-focal cerebellar glioblastoma multiforme and review the pathophisiology, clinical presentation, diagnosis and treatment of cerebellar glioblastomas.

glioblastoma multiforme; cerebellum; primary glioblastoma; p53; p73

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Podaci o izdanju

151 (6)

2009.

653-657

objavljeno

0001-6268

Povezanost rada

Temeljne medicinske znanosti

Indeksiranost