engleski

Comparison of clinical symptoms scored by the National Institutes of Health Chronic Prostatitis Symptoms Index (NIH-CPSI) and laboratory results for the assessment of clinical and bacteriological efficacy of antimicrobial treatment in patients with chronic prostatitis syndrome

We examined a total of 194 patients over 18 years of age with chronic prostatitis syndrome and no evidence of structural or functional lower genitourinary tract abnormalities. The following data were obtained for each patient: clinical history - the severity of chronic prostatitis symptoms scored by a Croatian translation of the NIH CPSI questionnaire, clinical status including digitorectal examination, urethral swab specimens, and selective samples of urine and EPS, according to the 4 - glass localization test (Meares and Stamey localization technique). Patients were treated orally with antimicrobial agents in doses and duration according to clinical practice in Croatia. An infectious etiology was determined in 169 (87%) patients. Chlamydia trachomatis was the causative pathogen in 38 (20%), Trichomonas vaginalis in 35 (18%), Enterococcus in 36 (19%) and Escherichia coli in 35 (18%) patients. In the remaining 25 patients the following causative pathogens were found: Ureaplasma urealyticum, Proteus mirabilis, Klebsiella pneumoniae, Streptococcus agalactiae and Pseudomonas aeruginosa. Comparison of symptoms scores and the effect on the quality of life has shown that most severe clinical presentation of disease was recorded in patients with chronic bacterial prostatitis caused by Escherichia coli and Enterococcus (p 0.001). Clinical success was paralleled by bacteriological eradication in chronic bacterial prostatitis caused by Chlamydia trachomatis, Enterococcus and Escherichia coli (kappa >0.2 0.5), but not in inflammatory chronic pelvic pain syndrome caused by Trichomonas vaginalis. * This research is part of a scientific research project of the Ministry of Science, Education and Sports of the Republic of Croatia: „ Diagnosis and treatment of patients with prostatitis syndrome“ (no. 143-1080002-0050)

chronic prostatitis syndrome

nije evidentirano