Hypoxia inducible factor-1α correlates with vascular endothelial growth factor A and C indicating worse prognosis in clear cel renal carcinoma (CROSBI ID 152982)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Đorđević, Gordana ; Matušan-Ilijaš, Koviljka ; Babarović, Emina ; Hadžisejdić, Ita ; Grahovac, Maja ; Grahovac, Blaženka ; Jonjić, Nives
engleski
Hypoxia inducible factor-1α correlates with vascular endothelial growth factor A and C indicating worse prognosis in clear cel renal carcinoma
The role of angiogenesis in the pathogenesis of renal cell carcinoma is well recognized, however, the influence of tumor cells in this activity has not yet been fully clarified. The aim of this study was to analyze the expression of hypoxia inducible factor-1α (HIF-1α ), a regulatory factor of angiogenic switch, in comparison to vascular endothelial growth factor A and C (VEGF-A and VEGF-C), recognized to be involved in blood and lymph vessel neoangiogenesis, with potential association in the prognosis of patients with renal cell carcinoma.
hypoxia inducible factor-1α ; VEGF A ; VEGF C ; clear cel renal carcinoma
Art. no. 40.
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Podaci o izdanju
28
2009.
40-1-40-8
objavljeno
0392-9078
10.1186/1756-9966-28-40