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In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test (CROSBI ID 553441)

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Mekić, Selma ; Šeol, Branka ; Matanović, Krešimir In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test // Microbes and Man-independence and future challenges. Gothenburg, 2009

Podaci o odgovornosti

Mekić, Selma ; Šeol, Branka ; Matanović, Krešimir

engleski

In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test

Background: Infections with antimicrobial-resistant bacteria are a great challenge in both human and veterinary medicine. Pseudomonas aeruginosa, an opportunistic, ubiquitous bacterial pathogen is becoming increasingly important due to its antibiotic resistance and ability to cause serious infections in animals and people. Objectives: Comparison of in vitro activities of enrofloxacin, ciprofloxacin, ticarcillin, ceftazidime, gentamicin and cefepime against 96 strains of P. aeruginosa isolated from dogs with otitis externa during the years from 1999 to 2008. Methods: Antimicrobial susceptibility was evaluated by E test1 in accordance with the guidelines of the National Committee for Clinical Laboratory Standards. Results: The most active compound in vitro was ceftazidime with 100% efficiency. The majority of tested strains were susceptible to ticarcillin (89.58%), followed by ciprofloxacin (87.50%), cefepime (58.33%) and gentamicin (56.25%). The highest resistance was observed towards enrofloxacin (53.13%), cefepime (33.33%), gentamicin (18.75%), ticarcillin (10.42%) and ciprofloxacin (9.38%). Only one strain (1.04%) showed sensitivity to enrofloxacin. Conclusions: This study showed that among all tested antimicrobial agents, ceftazidime was the most effective against P. aeruginosa strains. At the same time resistance to enrofloxacin was unexpectedly high.

Pseudomonas aeruginosa; E-test

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Podaci o prilogu

2009.

objavljeno

Podaci o matičnoj publikaciji

Microbes and Man-independence and future challenges

Gothenburg:

Podaci o skupu

FEMS 2009 3rd Congress of Euroean Microbiologists

poster

28.06.2009-02.07.2009

Göteborg, Švedska

Povezanost rada

Veterinarska medicina