In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test (CROSBI ID 553441)
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Podaci o odgovornosti
Mekić, Selma ; Šeol, Branka ; Matanović, Krešimir
engleski
In vitro activity of six antipseudomonal agents against Pseudomonas aeruginosa isolated from dogs with otitis externa determined by the E test
Background: Infections with antimicrobial-resistant bacteria are a great challenge in both human and veterinary medicine. Pseudomonas aeruginosa, an opportunistic, ubiquitous bacterial pathogen is becoming increasingly important due to its antibiotic resistance and ability to cause serious infections in animals and people. Objectives: Comparison of in vitro activities of enrofloxacin, ciprofloxacin, ticarcillin, ceftazidime, gentamicin and cefepime against 96 strains of P. aeruginosa isolated from dogs with otitis externa during the years from 1999 to 2008. Methods: Antimicrobial susceptibility was evaluated by E test1 in accordance with the guidelines of the National Committee for Clinical Laboratory Standards. Results: The most active compound in vitro was ceftazidime with 100% efficiency. The majority of tested strains were susceptible to ticarcillin (89.58%), followed by ciprofloxacin (87.50%), cefepime (58.33%) and gentamicin (56.25%). The highest resistance was observed towards enrofloxacin (53.13%), cefepime (33.33%), gentamicin (18.75%), ticarcillin (10.42%) and ciprofloxacin (9.38%). Only one strain (1.04%) showed sensitivity to enrofloxacin. Conclusions: This study showed that among all tested antimicrobial agents, ceftazidime was the most effective against P. aeruginosa strains. At the same time resistance to enrofloxacin was unexpectedly high.
Pseudomonas aeruginosa; E-test
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Podaci o prilogu
2009.
objavljeno
Podaci o matičnoj publikaciji
Microbes and Man-independence and future challenges
Gothenburg:
Podaci o skupu
FEMS 2009 3rd Congress of Euroean Microbiologists
poster
28.06.2009-02.07.2009
Göteborg, Švedska