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Regulatory effects of CD4 and CD8+ T lymphocytes on liver regeneration after partial hepatectomy in mice (CROSBI ID 464055)

Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija

Petković, Marija ; Ćuk, Mira ; Radošević-Stašić, Biserka ; Trobonjača, Zlatko ; Milin, Čedomila ; Verbanac, Donatella ; Dvornik, Štefica ; Ravlić-Gulan, Jagoda ; Muhvić, Damir ; Rukavina, Daniel Regulatory effects of CD4 and CD8+ T lymphocytes on liver regeneration after partial hepatectomy in mice // 4th International Congress on the Immune Consequences of Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches : Abstracts / Faist E (ur.). Bolonja: Monduzzi Editore, 1997. str. 515-520-x

Podaci o odgovornosti

Petković, Marija ; Ćuk, Mira ; Radošević-Stašić, Biserka ; Trobonjača, Zlatko ; Milin, Čedomila ; Verbanac, Donatella ; Dvornik, Štefica ; Ravlić-Gulan, Jagoda ; Muhvić, Damir ; Rukavina, Daniel

engleski

Regulatory effects of CD4 and CD8+ T lymphocytes on liver regeneration after partial hepatectomy in mice

The consequences of in vivo depletion of CD4+and/or CD8+ T lymphocytes on regenerating liver after partial hepatectomy (pHx) and the effects of pHx on intact and depleted lymphatic tissue were analysed. The results showed that depletion of CD8 and CD4+CD8 T lymphocytes significantly augment the content of RNA and proteins in early phase of regenerating liver. Removal of CD4+CD8 cells translocated also the peak of protein synthesis from 2nd to 1st post-Hx day. On the other hand, pHx stimulated the recovery of CD4+cells in CD4 depleted mice and augmented the proportion of CD8+ cells in both, CD8 and CD4+CD8 depleted mice.

liver regeneration; CD4 and/or CD8 depletion; hepatic DNA; RNA and proteins; mice

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Podaci o prilogu

515-520-x.

1997.

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objavljeno

Podaci o matičnoj publikaciji

4th International Congress on the Immune Consequences of Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches : Abstracts

Faist E

Bolonja: Monduzzi Editore

Podaci o skupu

4th International Congress on the immune consequences of trauma, shock and sepsis - mechanisms and therapeutic approaches

poster

04.03.1997-08.03.1997

München, Njemačka

Povezanost rada

Temeljne medicinske znanosti