Diversity of equine major histocompatiblity complex class II DRA locus in Posavina and Croatian Coldblood horse : a new polymorphism detected (CROSBI ID 161513)
Prilog u časopisu | kratko priopćenje | međunarodna recenzija
Podaci o odgovornosti
Arbanasić, Haidi ; Galov, Ana ; Salajpal, Krešimir ; Čurik, Ino
engleski
Diversity of equine major histocompatiblity complex class II DRA locus in Posavina and Croatian Coldblood horse : a new polymorphism detected
Domestic equidae display polymorphism within ELA-DRA locus which is not characteristic for other species. We characterised sequence polymorphism present at ELADRA locus exon 2 and estimated allele frequencies in two autochthonous breeds, Posavina and Croatian Coldblood. In 88 horses, four different alleles were found, one of them not reported before in horses. The new allele shows non-synonymous mutation at position 65 (T→A) causing amino acid change (Phe→Tyr) in antigen binding site and synonymous mutation at position 105 (C→T). Our findings emphasize the importance of DRA polymorphism among equids and some specific DRA frequency pattern potentially specific in draught horses.
DRA; SNP; Draught horse
Rad je prezentiran na skupu The 17th International Symposium "Animal Science Days", održanom u Padovi, Italija
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Podaci o izdanju
Povezanost rada
Veterinarska medicina, Poljoprivreda (agronomija), Biologija