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Pregled bibliografske jedinice broj: 457593

Časopis

Autori: Alebić, Miro Šimun; Duvnjak, Lea
Naslov: METABOLIC RISK MARKERS IN WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY
Izvornik: Diabetologia Croatica (0351-0042) 39 (2010), 1; 9-13
Vrsta rada: članak
Ključne riječi: polycystic ovary syndrome; polycystic ovarian morphology; metabolic risk markers; hyperandrogenism
Sažetak:
Polycystic ovary syndrome (PCOS) is a common endocrine condition in women of reproductive age, which is associated with a range of metabolic implications. Data concerning metabolic features of patients with polycystic ovarian morphology (POM) without any other PCOS diagnostic criteria (nonPCOS-POM) are limited. In the present study, metabolic profile of 46 women with nonPCOS-POM was investigated in comparison with 36 women with PCOS D phenotype and control group (N=146). PCOS D phenotype was defined according to the European Society for Human Reproduction and Embryology/American Society for Reproductive Medicine (ESHRE/ASRM) criteria as irregular anovulatory periods and POM. NonPCOS-POM patients in comparison to PCOS-D phenotype group showed a significantly lower waist circumference (73.0 ; 17.0 ; 99.5 ; 11.0 ; P<0.001), a homeostatic model assessment of insulin resistance (HOMA-IR) (1.1 ; 1.0 ; 12.8 ; 6.9 ; P<0.001) and a significantly higher fasting glucose-insulin ratio (FGIR) (15.2 ; 13.0 ; 5.9 ; 3.4 ; P<0.001). There was no significant difference in waist circumference, FGIR and HOMAIR between the nonPCOS-PMO and control group. As neither PCOS-D phenotype nor nonPCOS-POM patients are characterized by hyperandrogenism, our data suggest that hyperandrogenism is not the only factor contributing to the increased metabolic risk in women with PCOS D phenotype. NonPCOS-POM patients share a similar metabolic risk profile with the control population and could not be considered as patients with an increased metabolic risk.
Projekt / tema: 045-1080230-0516
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Scopus
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
Puni text rada: 457593.Diabetologia_Croatica_2010.pdf (tekst priložen 31. Ožu. 2010. u 14:22 sati)
URL cjelovitog teksta:
Časopis izlazi u samo elektroničkom izdanju: NE
Google Scholar: METABOLIC RISK MARKERS IN WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY
Upisao u CROSBI: lsmircic@mef.hr (lsmircic@mef.hr), 31. Ožu. 2010. u 14:22 sati



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