engleski

Markers of obesity and acute myocardial infarction

The role of obesity as independent risk factor for cardiovascular disease (CVD) is well known. Waist circumference (WC), waist-to-hip ratio (WHR) and body mass index (BMI) are widely used indicators of abdominal obesity. The aims of this study were to determine markers of obesity and to investigate relation between them and coronary risk factors in patients with acute myocardial infarction (AMI). The study included 148 patients, 104 men and 44 women, aged on average 62, 28 (59, 46 men and 68, 93 women) years, hospitalized in CCU between April and October 2006. Subjects were classified into 2 groups: 1. AMI with ST elevation (STEMI) and 2. AMI without ST elevation (NSTEMI). BMI, WC, WHR, arterial hypertension (AH), smoking, cholesterol, triglycerides, LDL-C and HDL-C were measured. STEMI and NSTEMI group comparison showed higher triglycerides level in STEMI patients (P=0.004) and higher prevalence of AH (P=0.02). STEMI group differed from all patients concerning age (younger, P=0.01), weight (more weight, P=0.001), LDL-C (lower level, P=0.003) and AH (higher prevalence, P=0.04). NSTEMI group differed from all patients concerning weight (lesser weight, P=0.04), waist (larger waist, P=0.04), cholesterol (higher level, P=0.04) and LDL-C (higher level, P=0.001). Data suggest that relations of markers of obesity as risk factors for CVD are opposite to previous studies. Important risk factors for STEMI were larger weight and younger age and for NSTEMI larger waist, higher cholesterol and LDL-c. Most significant finding using bivariate correlation analysis was positive correlation between WHR and cholesterol (R=0.31) in STEMI group.

obesity ; myocardial infarction

DOI: 10.1016/S1567-5688(07)71661-6