engleski

Hematological and biochemical reference intervals in Dalmatian pramenka sheep estimated from reduced sample size by bootstrap resampling

Monitoring of health status in organic farming relies in part on the availability of exact reference intervals for key hematological and biochemical blood parameters. Once determined, these intervals provide a baseline for interpreting routine laboratory blood tests in order to assess nutritional status, stress or disease. In this work, reference intervals for hematological and blood biochemical parameters were determined for Dalmatian pramenka, an indigenous Croatian sheep breed. A recently developed nonparametric method based on bootstrap resampling was used for calculation of reference intervals, and its performance was compared with that of a conventional nonparametric method. Hematological and blood biochemical profiles from 114 organically reared Dalmatian premenka sheep were constructed and used for calculation of reference intervals using the novel approach. The new method enabled convenient and reliable determination of reference intervals from a relatively small sample size, without the need for transformation or filtering of the raw data. Separate reference ranges for male and female sheep were found to be unnecessary for most of the investigated parameters.

reference interval; bootstrap; biochemistry; hematology; sheep; pramenka

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