Cholesterol effect on formation of amyloid-b peptide upon NPC1 dysfunction (CROSBI ID 567942)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Malnar, Martina ; Košiček, Marko ; Goate, Alison ; Hećimović Silva
engleski
Cholesterol effect on formation of amyloid-b peptide upon NPC1 dysfunction
In this work we showed that cholesterol accumulation upon dysfunction of the cholesterol transport protein NPC1 leads to increased APP cleavage by beta-secretase and thus amylid-beta generation, a key molecule in the pathogenesis of Alzheimer's disease.
Alzheimer's disease; cholesterol; APP protein; Abeta peptide; NPC1
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Podaci o prilogu
29-29.
2008.
objavljeno
Podaci o matičnoj publikaciji
Workshop Adenoviruses Basic to Gene Therapy : programme and abstracts
Majhen, Dragomira ; Ambriović Ristov, Andreja
Zagreb: Hrvatsko mikrobiološko društvo
978-953-96567-6-6
Podaci o skupu
Workshop Adenoviruses Basic to Gene Therapy
poster
24.09.2008-27.09.2008
Zadar, Hrvatska
