engleski

Extent of DNA damage in rats' kidney, liver and brain after GSM electromagnetic radiation

Objective of investigation was to assess DNA damage in rat’s renal, liver and brain cells after in vivo exposure to radiofrequency/microwave (Rf/Mw) radiation of cellular phone frequencies. Single cell gel electrophoresis/comet assay was used to determine DNA damage. Wistar rats (N=9) were exposed to the carrier frequency of 915 MHz with Global System Mobile signal modulation (GSM), power density 2.4 W/m2, whole body average SAR 0.6 W/kg. The irradiation lasted one hour/day, seven days/week during two weeks period. Exposure set-up was Gigahertz Transversal Electromagnetic Mode Cell (GTEM-cell) equipped by tracking generator and signal amplifier. The temperature in the GTEM-cell was maintained at 37 0C. Sham-irradiated controls (N=9) were a part of the study. The body temperature was measured before and after exposure. No difference in temperature between control and treated animals was observed. The tail length and tail intensity were evaluated. In comparison with sham controls, the tail length was slightly elongated in brain cells of irradiated animals and notably differs in liver and kidney cells. Differences in tail intensity between control and exposed animals were not significant. To conclude, applied Rf/Mw radiation might cause DNA breaks in alkali-labile sites in renal, liver and brain cells after rats’ whole-body irradiation.

in vivo; cellular phone frequencies; GTEM-cell; comet assay

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