engleski

Metabolic Profiling to Assess Health Status

Dairy cows undergo enormous metabolic adaptation around parturition to support lactation. The regulation of glucose, lipid and protein metabolism among liver, adipose tissue, muscles and mammary gland is the crucial component of this adaptation. The liver has a central role in these adaptive mechanisms, including gluconeogenesis and metabolism of fatty acids mobilized from adipose tissue. Lipid infiltration may impair liver functions and increase susceptibility to periparturient health problem. Metabolic disorders could contribute to poor health status and reproductive disorders in advanced lactation. The metabolic dynamics in transition period should be taking into consideration during metabolic profiling. Main diagnostic analytes identified as predictive for health problem in transition dairy cow include NEFA, beta-hydroxybutyrate, cholesterol, albumin and macrominerals. Metabolic profile, its appropriate interpretation and good understanding of pathophysiological processes involved in the metabolic adaptation have an important role in monitoring health status of cows. Moreover, only the team approach will make the metabolic profile a useful tool providing valuable diagnostic information.

metabolic profiling, dairy cows, health status

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