Preoperative antiseptics in clean/contaminated maxillofacial and oral surgery : prospective randomized study (CROSBI ID 168694)
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Podaci o odgovornosti
Košutić, Damir ; Uglešić, Vedran ; Perković, Dunja ; Peršić, Zdenka ; Šolman, Lea ; Lupi-Ferandin, Slaven ; Knežević, Predrag ; Sokler, Klara ; Knežević, Goran
engleski
Preoperative antiseptics in clean/contaminated maxillofacial and oral surgery : prospective randomized study
In order to show the effectiveness of preoperative antiseptics mouthwash the authors undertook a prospective study in 120 patients who uderwent elective surgery under general or local anesthesia. Patients were allocated toone of 4 groups, depending on whether the oral cavity was washed preoperatively with 1% cetrimide, chlorhexidine, povidon-iodine or sterilized normal saline solution (control group). Aerobic and anaerobic bacterial samples were taken from the inferior vestibulum mucosa before surgery, 5 min after the start of the operation and at the end of the procedure. The results show a statistically significant reduction in bacterial counts during procedures in which antiseptics are used to wash the oral cavity preoperatively. 1% cetrimide solution was the most successful in reducing intra-oral bacterial counts and produced the longest lasting antiseptic effect. Chlorhexidine is a good option for procedures longer than 1 hour, while povidon-iodine is recommended for procedures lasting up to 1 hour. Normal saline reduced bacterial counts in the specimen taken 5 min after washing but this short-lasting effect is due to mechanical cleansing rather than the antiseptic effect.
preoperative oral cavity washing ; antiseptics ; bacterial counts reduction ; intraoral surgery ; postoperative infections
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Podaci o izdanju
38 (2)
2009.
160-165
objavljeno
0901-5027
10.1016/j.ijom.2008.11.023
Povezanost rada
Kliničke medicinske znanosti