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Synthesis, x-ray and spectroscopic analysis of 2- hydrazino-6-methyl-4(methoxymethyl)-5- nitropyridine-3-carbonitrile

Our previous work was focused on systematic research of synthesis and analysis of heterocyclic molecules. As a part of that research, present work continues the characterization of various bioactive derivatives of pyridines and their metal complexes. Pyridine derivatives have interesting pharmacological properties and are reported to possess many biological activities such as antibacterial, antifungal, antiviral and antitumor. The type of biological activity is influenced by pyridine ring substituents. 2- hydrazino-6-methyl-4-(methoxymethyl)-5- nitropyridine-3-carbonitrile was synthesized and confirmed by single crystal X-ray diffraction method and corresponding molecular structure was experimentally characterized by means of IR, 1H- NMR, 13C-NMR and UV-vis spectroscopy techniques. UV-vis absorption and emission spectra of the compound were recorded in protic and aprotic solvents at 25 °C. Spectra of aqueous solution were also recorded at different temperatures and pH values and protonation constant was calculated.

Substituted pyridine; X-ray diffraction; IR; NMR; UV-vis spectroscopy.

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