engleski

Congenital peromelia in Simental calf

In a female Simental calf monobrachial peromelia in the right front limb was observed. Peromelia is a rare but mutilating congenital deformity representing failure of formation of parts of the upper limb. The deformity is presented unilaterally in the vast majority of the cases. The malformation is peromelia and occurs in a familiar pattern. The defect seems to have an autosomal recessive mode of inheritance with variation in the expressivity of the genotype. It condition might be characterized by agenesia of the phalanges and parts of the metacarpus or metatarsus affecting one or more limbs. In some cases additional skeletal defects were found. Possible genetic and environmental causes of this rare congenital anomaly are discussed in the context of congenital limb anomalies in cattle. Defects in the expression of genes responsible for development of the distal limb could be involved in the pathogenesis of this type of peromelia observed

peromelia; tele

nije evidentirano