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izvor podataka: crosbi

REVIGO summarizes and visualizes long lists of Gene Ontology terms (CROSBI ID 172196)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Supek, Fran ; Bošnjak, Matko ; Škunca, Nives ; Šmuc, Tomislav REVIGO summarizes and visualizes long lists of Gene Ontology terms // PLoS One, 6 (2011), 7; e21800-e21800. doi: 10.1371/journal.pone.0021800

Podaci o odgovornosti

Supek, Fran ; Bošnjak, Matko ; Škunca, Nives ; Šmuc, Tomislav

engleski

REVIGO summarizes and visualizes long lists of Gene Ontology terms

Outcomes of high-throughput biological experiments are typically interpreted by statistical testing for enriched gene functional categories defined by the Gene Ontology (GO). The resulting lists of GO terms may be large and highly redundant, and thus difficult to interpret. REVIGO is a Web server that summarizes long, unintelligible lists of GO terms by finding a representative subset of the terms using a simple clustering algorithm that relies on semantic similarity measures. Furthermore, REVIGO visualizes this non-redundant GO term set in multiple ways to assist in interpretation: multidimensional scaling and graph-based visualizations accurately render the subdivisions and the semantic relationships in the data, while treemaps and tag clouds are also offered as alternative views. REVIGO is freely available at http://revigo.irb.hr/.

Gene Ontology; visualization; enrichment; graph; semantic similarity; redundancy

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Podaci o izdanju

6 (7)

2011.

e21800-e21800

objavljeno

1932-6203

10.1371/journal.pone.0021800

Povezanost rada

Računarstvo, Biotehnologija, Biologija

Poveznice
Indeksiranost