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Pregled bibliografske jedinice broj: 530176

Časopis

Autori: Polšek, Dora; Jagatić, Tomislav; Cepanec, Maja; Hof, Patrick; Šimić, Goran
Naslov: Recent developments in neuropathology of autism spectrum disorders
Izvornik: Translational neuroscience (2081-3856) 2 (2011), 3; 256-264
Vrsta rada: pregledni rad
Ključne riječi: autism; autism spectrum disorders
Sažetak:
Autism spectrum disorders (ASD) represent complex neurodevelopmental disorders characterized by impairments in reciprocal social interactions, abnormal development and use of language, and monotonously repetitive behaviors. With an estimated heritability of more than 90%, it is the most strongly genetically influenced psychiatric disorder of the young age. In spite of the complexity of this disorder, there has recently been much progress in the research on etiology, early diagnosing, and therapy of autism. Besides already advanced neuropathologic research, several new technological innovations, such as sleep functional MRI, diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy imaging ( 1 H-MRS) divulged promising breakthroughs in exploring subtle morphological and neurochemical changes in the autistic brain. This review provides a comprehensive summary of morphological and neurochemical alterations in autism known to date, as well as a short introduction to the functional research that has begun to advance in the last decade. Finally, we mention the progress in establishing new standardized diagnostic measures and its importance in early recognition and treatment of ASD.
Projekt / tema: 108-1081870-1942, 013-1081870-2627
Izvorni jezik: ENG
Rad je citiran u
bazama podataka:
Scopus
Web of Science: Science Citation Index Expanded
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti,Pedagogija
URL Internet adrese: http://www.springerlink.com/content/4674u2782886q42q/
Broj citata:
Altmetric:
DOI: 10.2478/s13380-011-0024-3
URL cjelovitog teksta: SpringerLink
Google Scholar: Recent developments in neuropathology of autism spectrum disorders
Upisao u CROSBI: mcepanec@erf.hr (mcepanec@erf.hr), 13. Lis. 2011. u 15:05 sati



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