The impact of prepregnancy BMI and weight gain during pregnancy on pregnancy outcome among women with GDM. (CROSBI ID 577889)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Juras, Josip ; Ivanisević, Marina ; Herman, Mislav ; Horvatiček, Marina ; Anzulović, Dunja
engleski
The impact of prepregnancy BMI and weight gain during pregnancy on pregnancy outcome among women with GDM.
Introduction. Obesity is one of risk factors for impaired glucose metabolism, preeclampsia and adverse pregnancy outcome. Prepregnancy body mass index correlates with perinatal outcome, but weight gain during pregnancy seems to have an important influence on birth weight. Aim. The aim of this study was to explore weather prepregnancy BMI or weight gain during pregnancy had bigger influence on perinatal outcome among GDM women vs. controls. Materials and methods. This is a historical cohort study. The data of one decade period till 2010 from our clinic was analyzed. It included 3741 singleton pregnancies. Women were divided into 4 subgroups according to their diagnosis and prepregnancy BMI. Results. Both BMI and maternal weight gain were positively correlated to neonatal birth weight, but weight gain had bigger correlation coefficient than BMI (r=0.256, r=0.158 ; p<0.001, respectively). There was a statistically significant difference between subgroups in birth weight and ponderal index. The biggest birth weight and ponderal index had children form GDM mothers with BMI ≥25, the smallest were in control group with BMI <25. The results of standard multiple linear regression showed that maternal weight gain had higher influence to birth weight than BMI (R2=0.011, ΔR2=0.114 ; p<0.001). GDM women with BMI ≥25 had the highest rate of macrosomic neonate (30.1%) among other groups (χ2=103.053 ; p<0.001). The rate of preterm birth was likewise highest (9.2%, χ2=12.92 ; p=0.005). According to greater weight gained women had macrosomic neonate more often. The likelihood ratio for women who gained 10-16 kilos was 0.895, but with 20-24 and 24-30 kilos gained rates were 1.577 and 2.965, respectively. Having GDM there is 1.61 RR of having macrosomic neonate in relation to control group. GDM women with BMI ≥25 had 1.49 RR (95% CI 1.41 – 1.85 ; p<0.001) for macrosomic child in relation to GDM women with BMI <25 (95% CI 1.22 – 1.81 ; p<0.001). Conclusion. Considering BMI and weight gain as predictor parameters for perinatal outcome it can be concluded that weight gain has higher predictive value compared to BMI. Women with larger BMI and weight gain have more adverse perinatal outcome and is getting poorer as BMI and weight continue to rise.
pregnancy; weight gain; gestational diabetes mellitus
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Podaci o prilogu
41-41.
2011.
objavljeno
Podaci o matičnoj publikaciji
XXXIII Alpe Adria Meeting of Perinatal Medicine
Đelmiš, Josip ; Ivanišević, Marina ; Juretić, Emilja
Zagreb: Hrvatsko društvo za perinatalnu medicinu HLZ-a
953645179-1
Podaci o skupu
XXXIII Alpe Adria Meeting of Perinatal Medicine
predavanje
30.09.2011-01.10.2011
Zagreb, Hrvatska