engleski

On statistical properties of palindromes in DNA

The main aim of this paper is to determine the distribution of palindromes of a xed length in a DNA sequence. Palindrome in DNA is a part of the DNA sequence which is equal to its complementary sequence read backwards (C~G, A~T). We examine general case where the probability of occurrence of each nucleobase is arbitrary (with condition that they sum to one). Also, we determine conditions in which normal approximation can be used. Special attention is given to coding and noncoding regions in DNA and to distribution of bases in those parts of DNA. Some real genomes are considered and analysed in details.

palindromes in DNA; m-dependent sequence; Normal distribution

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