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izvor podataka: crosbi

Bacterial colonization or infection in chronic sinusitis (CROSBI ID 180440)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Pandak, Nenad ; Pajić-Penavić, Ivana ; Sekelj, Alen ; Tomić-Paradžik, Maja ; Čabraja, Ivica ; Miklaušić, Božana Bacterial colonization or infection in chronic sinusitis // Wiener klinische Wochenschrift, 123 (2011), 23/24; 710-713. doi: 10.1007/s00508-011-0093-x

Podaci o odgovornosti

Pandak, Nenad ; Pajić-Penavić, Ivana ; Sekelj, Alen ; Tomić-Paradžik, Maja ; Čabraja, Ivica ; Miklaušić, Božana

engleski

Bacterial colonization or infection in chronic sinusitis

The aim of this study was the determination of bacteria present in maxillary and ethmoid cavities in patients with chronic sinusitis and to correlate these findings with bacteria simultaneously present in their nasopharynx. The purpose of this correlation was to establish the role of bacteria found in chronically inflamed sinuses and to evaluate if the bacteria present colonized or infected sinus mucosa. Nasopharyngeal and sinus swabs of 65 patients that underwent functional endoscopic sinus surgery were cultivated and at the same time the presence of leukocytes were determined in each swab. The most frequently found bacteria in nasopharynx were Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus spp., Streptococcus viridans and Streptococcus pneumoniae. Maxillary or ethmoidal sinus swabs yielded bacterial growth in 47 (72.31%) patients. The most frequently found bacteria in sinuses were Staphylococcus epidermidis, Staphylococcus aureus, Klebsiella spp. and Streptococci (pneumoniae, viridans and spp.). The insignificant number of leukocytes was present in each sinus and nasopharyngeal swab. Every published microbiology study of chronic sinusitis proved that sinus mucosa were colonized with bacteria and not infected, yet antibiotic therapy was discussed making no difference between infection and colonization. Chronic sinusitis should be considered a chronic inflammatory condition rather than bacterial infection, so routine antibiotic therapy should be avoided. Empiric antibiotic therapy should be prescribed only in cases when the acute exacerbation of chronic sinusitis occurs and the antibiotics prescribed should aim the usual bacteria causing acute sinusitis. In case of therapy failure, antibiotics should be changed having in mind that under certain circumstances any bacteria colonizing sinus mucosa can cause acute exacerbation of chronic sinusitis.

bacterial colonization ; infection ; chronic sinusitis

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Podaci o izdanju

123 (23/24)

2011.

710-713

objavljeno

0043-5325

10.1007/s00508-011-0093-x

Povezanost rada

Kliničke medicinske znanosti

Poveznice
Indeksiranost